The Bloody Marys is a superhero-inspired comedic tale of two reluctant heroes who discover spectacular powers attached to their menstrual cycles. One has super strength, the other has psychic abilities and both have explosive force periods; the power of which can be harnessed to fly, to jump, and to drown enemies.

Together with the Moon Goddess, their guide in all things super, the Marys fight the subtle and blatant misogynist threats of Condo Town.